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NFL Betting Tips: San Francisco 49ers vs. Kansas City Chiefs Preview and Picks


The stakes will be higher for the San Francisco 49ers when they host the Kansas City Chiefs this Sunday in a rematch of last February’s Super Bowl.

The Niners have lost three of their last five games and have battled several injuries that have weakened their skill position.

Kyle Shanahan’s team improved their record to 3-3 with a dominant 36-24 win over the Seattle Seahawks last Sunday while the Chiefs were resting on their bye week.

Kansas City is one of two remaining undefeated teams in the NFL, posting a 5–0 record after defeating the New Orleans Saints 26–13 at Arrowhead Stadium.

But Andy Reid’s men have also faced injury problems, as wide receivers Hollywood Brown and Rashee Rice are both expected to miss the remainder of the season, as leading rusher Isiah Pacheco continues to recover from a fractured fibula on injured reserve.

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NFL Betting Tips: San Francisco 49ers vs. Kansas City Chiefs betting tips

  • Kansas City Chiefs – Money Line @ 1/1
  • Total Marks – Less than 47.5 @ 20/23

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The Chiefs have history on their side

The Chiefs coped admirably against the Saints without Brown, Rice and Pacheco, racking up 460 yards of offense and dominating time of possession by a ratio of two to one.

And while Patrick Mahomes and Travis Kelce stay healthy, they’ll always have a chance.

Mahomes has upset the 49ers in two Super Bowls and won the game’s MVP award both times.

And until Shanahan finds a defensive scheme that works against the Texans triggerman, the Chiefs should be favored in these contests.

However, they are marginal underdogs for this trip to Levi’s Stadium – although Super Bowl winners are historically 6-3 in next season’s rematch.

Further proof that the Chiefs are worth supporting on the money line comes from the fact that Mahomes excels when an underdog and Reid’s teams are nearly undefeated after the bye week.

Mahomes has won 10 of 13 games when the Chiefs were not favored, covered the spread in 11, and averaged the most passing yards per game (301.7) of any QB as an underdog since 1970 (With minimum 10 starters).

Reed is 21-4 after their bye week, the best mark by a coach since 1970.

Opponent defense can keep scoring down

San Francisco’s injury problem appears to be worsening with backup RB Jordan Mason and key wide receiver Juwan Jennings missing practice this week.

Star rusher Christian McCaffrey has not played a game all season and Deebo Samuel has been limited in practice due to a wrist injury.

If Mason can’t hold up against the Chiefs, fourth-round draft pick Isaac Guerrando will be the next man in the backfield, while fellow rookie Ricky Pearsall, who was the victim of a shooting during an attempted armed robbery a week before the regular season started . , is set to make his first NFL appearance as a wide receiver.

The Niners’ defense gives them the best chance to win this game as they currently rank seventh in the league against the run and outside the top 10 in opposition yards per game.

However, the Chiefs defense is every bit as good – if not better. Steve Spagnuolo’s unit currently ranks fourth in the league in yards per rush allowed and is in the top half of the league in yards per pass attempt.

Taking the point total down to 47.5 from when they last met in February, it looks to be a solid game amid the current injury situation of both teams.

All possibilities are correct at the time of writing

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